Best hot spot medication for dogs

Nala has allergies, and like many Bassets, keeping his ears clean and infection-free is a constant challenge. Sometimes we fall behind, and he needs medication for his ears. Recently, while treating him with ear drops and an oral antibiotic, he developed a hot spot between his toes that he won’t stop bothering. He went back to the vet and now, long story short, he’s on two antibiotics, prednisone, Benadryl, ear ointment, and wearing a cone. He is miserable, and I feel terrible, but he still won’t leave the spot alone. Bitter apple isn’t working. I have tried putting a sock on his paw, but it comes off, and it needs to stay dry anyway. Any suggestions would be greatly appreciated! Thank you.